Article snapshot:
It’s important to keep an eye on liver function tests like ALP and bilirubin
The normal range for ALP is 44 to 147 IU/L
The normal range for total bilirubin is 0.1 to 1.2 mg/dL
Working with your doctor to reach these ranges may prevent PBC progression
As someone with primary biliary cholangitis (PBC), you are likely familiar with alkaline phosphatase (ALP) levels, since high ALP levels are usually an early sign of PBC. But if you’re like many people with PBC, you may not really know what the normal ALP range is or what to look for.
We’ve created a guide to ALP––what your doctor may call “Alk Phos”––as well as other markers important to PBC. Being more informed may help you better understand your own test results.
Liver Function Tests in PBC
Liver function tests (LFTs) are blood tests that measure different markers found in your liver to provide information on how well your liver is working. In addition, these lab tests can help your doctor determine if any treatment you are taking for PBC is working.
The most telling tests in PBC are ALP and bilirubin. If there is a change in either of these levels in your labs, talk to your doctor about what it might mean.
Tests that measure liver inflammation include aspartate aminotransferase (AST) and alanine transaminase (ALT).
While these levels are all important to keep track of, it’s especially important to keep an eye on ALP, as a high level that stays consistently elevated over time should be discussed with your doctor.
Normal Ranges in Liver Function Tests
While sometimes normal ranges can vary depending on the lab, below are what are considered normal ranges for ALP and bilirubin.
It's likely that you are having your liver markers tested regularly and checked by your doctor. If your numbers are remaining high over time, or aren’t within these ranges, discuss them with your doctor to see what can be done.
Why Lowering High ALP Is a Goal
While it may seem okay for high ALP levels to stay the same over time, the fact is that consistently high ALP levels should be discussed with your doctor.
This information is not intended to be medical advice. Any medical concerns or questions regarding PBC should be discussed with your doctor.
